What have humans gained from animal testing? Are we getting closer to finding a cure for HIV, cancer, and other diseases through animal experiments? These 11 animal testing statistics will help you understand how animal experiments (don’t) work and what we’re (not) getting out of them.

1. Each year, more than 110 million animals—including mice, frogs, dogs, rabbits, monkeys, fish, and birds—are killed in U.S. laboratories.

Experimenters force animals to inhale toxic fumes, immobilize them in restraint devices, drill holes into their skulls, mutilate their brains, and burn their skin and eyes—and if the animals don’t die in the process, they’re killed afterward. Whether it’s for biology lessons, medical training, curiosity-driven experiments, or chemical, drug, food, or cosmetics testing, these animals are confined to barren cages, socially isolated, and psychologically traumatized.

Covance Cruelty

2. Ninety-five percent of all drugs that are shown to be safe and effective in animal tests fail in human trials.

This stat comes straight from the National Institutes of Health (NIH)—the government agency that funnels billions of our taxpayer dollars into these reckless experiments. NIH has noted that the drugs fail in humans because they either don’t work or are dangerous. Because animal trials are so unreliable, they make human ones more risky.

animal testing statistics

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3. Ninety-nine percent of the animals used in laboratories aren’t covered by federal animal protection laws.

It’s as if the government were saying, “I’m sorry, but you’re just not animal enough” to the tens of millions of rats, mice, birds, fish, reptiles, and amphibians who constitute 99% of the animals used in laboratories yet are excluded by the federal Animal Welfare Act (AWA) and therefore denied even the most basic consideration. However, even animals who are supposedly “protected” under the AWA are still allowed to be burned, shocked, poisoned, isolated, starved, restrained, made addicted to drugs, and brain-damaged. No test—no matter how painful or trivial—is illegal. And pain relief isn’t required.

© Doctors Against Animal Experiments

4. Between 2015 and 2019, more than 300,000 animals covered under the AWA were subjected to painful experiments without pain relief.

Rabbits haven’t received any pain relief in the Draize eye and skin irritation and corrosion tests since they started in the 1940s. In these tests, a substance is dripped into rabbits’ eyes or smeared onto their shaved skin, leaving them to suffer from inflammation, ulcers, bleeding, irritated and cloudy eyes, blindness, redness, swelling, discharge, and hemorrhaging.

5. A 2009 survey found that mice and rats used in invasive, painful surgeries were only provided with post-operative pain relief about 20% of the time.

The survey found that mice and rats who were subjected to skull surgeries, burn experiments, spinal surgeries, and other horrors rarely received post-procedural pain relief. Imagine someone drilling open your skull to expose your brain but not giving you so much as an Advil.

animal testing statistics

6. More than 93% of experimental cancer drugs failed in the first phase of human clinical trials after testing “successfully” on animals.

The survey was based on nearly 4,500 cancer drugs developed between 2003 and 2011. Artificially inducing a condition in a healthy individual of a different species who is confined and isolated in stressful, unnatural conditions and then applying the results to naturally occurring diseases in humans is not only unethical but also ridiculous. Even animal experimenters acknowledge that the extreme distress that these animals endure jeopardizes the results.

We’ve been handicapped by the fact that we have been studying diseases in animals that don’t really exist in animals. Mice … don’t get schizophrenia. They don’t get Alzheimer’s disease.

—Dr. Christer Nordstedt, Eli Lilly’s vice president of neuroscience research

7. The chemicals that cause cancer in rats only cause it in mice 46% of the time.

If extrapolating from rats to mice is so unreliable, imagine the inefficiency of applying results from mice, rats, rabbits, dogs, and monkeys to humans. Richard Klausner, former head of the National Cancer Institute, said, “The history of cancer research has been a history of curing cancer in the mouse. We have cured mice of cancer for decades and it simply didn’t work in humans.”

8. One hundred HIV vaccines have been successful in animal experiments—100% of them failed to protect humans sufficiently.

In one case, an HIV vaccine that was shown to be effective in monkeys failed in human clinical trials because it didn’t prevent people from developing AIDS, and some believe that it made them more susceptible to it. According to a report in The Independent, one conclusion was that “testing HIV vaccines on monkeys before they are used on humans, does not in fact work.”

Monkeys used for experiments are often housed inside tiny and virtually barren cages for their entire lives, deprived of everything that’s natural and important to them.

 9. Every year in the U.S., NIH blows about 47% of research funding on animal experimentation.

Approximately 47% of NIH-funded research involves animals, and in 2020, the agency budgeted nearly $42 billion for research and development—that’s $19.6 billion spent on animal experiments. But for what? Do you know of any cures for multiple sclerosis, West Nile virus, or muscular dystrophy? Well, there aren’t any. A 2014 review paper co-authored by a Yale School of Medicine professor in The BMJ documented the overwhelming failure of experiments on animals to improve human health, concluding that “the public’s continuing endorsement and funding of preclinical animal research seems misplaced.”

10. Currently, 52% of U.S. adults oppose the use of animals in scientific research.

A Pew Research Center poll found that the majority of American adults oppose the use of animals in scientific research, and other surveys suggest that the misguided folks who do support it only feel that way because they wrongly believe that it’s necessary. In an article published in The Journal of the American Medical Association, researchers found that medical treatments developed for animals rarely translated to humans and warned that “patients and physicians should remain cautious about extrapolating the finding of prominent animal research to the care of human disease … poor replication of even high-quality animal studies should be expected.”

animal testing statistics

11. Since 2017, PETA U.S. has had nearly 150 victories for animals used in experiments.

Our victories include helping engineers develop a new ventilator for COVID-19 patients without animal testing, working with the Taiwan Food and Drug Administration to eliminate animal tests for health marketing claims for foods, persuading Suave to go cruelty-free, and getting pharma giant Bristol Myers Squibb and others to ban near-drowning tests. PETA entities’ work to end animal experiments—backed by the support of more than 9 million members and supporters worldwide—is saving countless animals.


In NIH’s most recent five-year plan, the agency stated that “animal models often fail to provide good ways to mimic disease or predict how drugs will work in humans, resulting in much wasted time and money while patients wait for therapies.” Animal experiments are not a good indicator of drug responses in humans or any species other than the one being exploited. Penicillin is the backbone of human antibiotics, yet it kills guinea pigs! Aspirin kills cats and causes birth defects in rats, mice, guinea pigs, dogs, and monkeys, and morphine, a depressant in humans, stimulates goats, cats, and horses.

All these animal testing statistics can be boiled down to just one: Animal experiments are speciesist—making them unacceptable 100% of the time. They don’t work, and even if they did, they’d still be unacceptable. Torturing sensitive beings isn’t OK, even if someone’s pretending it’s for science or medicine—it’s as simple as that.

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 Ingrid E. Newkirk

“Almost all of us grew up eating meat, wearing leather, and going to circuses and zoos. We never considered the impact of these actions on the animals involved. For whatever reason, you are now asking the question: Why should animals have rights?” READ MORE

— Ingrid E. Newkirk, PETA President and co-author of Animalkind